منابع مشابه
Novel characteristics of alpha-fetoprotein (AFP)-producing gastric cancer
Background Although serum AFP level is increased in the AFP-producing gastric cancer (GC) patient, AFP-producing GC may become recurrent without re-elevation of serum AFP level. Therefore, novel characteristics of AFP-producing GC such as other biomarkers are to be explored. Results 35 AFP-GC and 48 non-AFP-GC patients were included. Our present study revealed that blood type O (15 cases, 42....
متن کاملAFP (alpha fetoprotein): who are you in gastrology?
AFP-producing (hepatoid differentiation) gastric cancer (GC) initially reported in 1970 plays an important role in the field of gastrology, which should be distinguished from other solid-type GCs owing to their different biological behavior. This review article aims to summarize the literature related to the role of AFP in gastric cancer and to unveil the underlying mechanism by which AFP-produ...
متن کاملAlpha-fetoprotein (AFP) and Chromosomal/Genetic Instability Disorders: Is AFP a Reporter Protein for DNA Damage-Sensing and Repair?
Many cancer cells exhibit an unstable genome resulting from chromosomal aberrations and gene mutations in somatic cells which generate heterogeneous cell populations manifesting diseases such as cancer. Genomic/chromosomal instability can arise from non-repaired broken DNA along the chromosome or from loss of telomeric ends of chromosomes. Normally, DNA single or double-stranded breaks are repa...
متن کاملHereditary Persistence of Alpha-Fetoprotein Is Associated with the −119G>A Polymorphism in AFP Gene
Alpha-fetoprotein (AFP) is a glycoprotein that is produced by the liver and yolk sac during fetal development. Its levels are usually raised in malignant conditions. Hereditary persistence of AFP (HPAFP) is a rare benign condition with elevated levels of AFP. It is inherited in a dominant mode with complete penetrance and is usually not associated with any clinical disability. We report two ind...
متن کاملMapping of the porcine alpha-fetoprotein (AFP) gene to swine chromosome 8.
References 1 Clore G. et al. (1989) J Biol chem 15, 18907–11. 2 Goodman R. et al. (1992) Biochemistry 31, 10483–90. 3 Hu Z. et al. (1997) Mamm Genome 8, 246–9. 4 Suzuki K. et al. (2000) Animal Genetics 31, 8–12. 5 Mukaida N. et al. (1989) Journal of Immunology 143, 1366– 71. 6 Ishikawa J. et al. (1993) Gene 131, 305–6. 7 Mikawa S. et al. (1999) Animal Genetics 30, 407–17. 8 Manly K.F. (1993) Ma...
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ژورنال
عنوان ژورنال: Atlas of Genetics and Cytogenetics in Oncology and Haematology
سال: 2013
ISSN: 1768-3262
DOI: 10.4267/2042/48465